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On line 129, column 72 <!DOCTYPE html> <html class="no-js" lang="en-us"> <head> <meta http-equiv="X-UA-Compatible" content="IE=Edge" /> <meta charset="utf-8" /> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <!-- Begin /common/zf6/meta/seo.ftl --> <meta name="robots" content=""/> <link rel="canonical" href=""/> <meta name="title" content="The Charles and Jane Pak Center for Mineral Metabolism and Clinical Research - UT Southwestern, Dallas, Texas"/> <title>The Charles and Jane Pak Center for Mineral Metabolism and Clinical Research - UT Southwestern, Dallas, Texas</title> <meta name="description" content="Mineral Metabolism provides excellence in the clinical care of patients with diseases of mineral metabolism; advances medical knowledge of the causes and treatments of these diseases; and educates physicians."/> <meta name="language" content="en-US"/> <meta name="gsa:thumbimage:src" content="https://www.utsouthwestern.edu/resources/images/UTSW_icon.jpg" /> <!-- Elasticsearch META --> <meta name="es:modified" content="2024-03-22T08:43:39.554-0500"/> <meta class="elastic" name="es_modified" content="2024-03-22T13:43:39Z"/> <meta name="es:launchDate" content=""/> <meta name="es:tags" content=""/> <meta name="es:type" content="article" /> <meta class="elastic" name="es_type" content="article" /> <meta name="es:author" content=""/> <meta name="es:thumbimage:rendition" content=""/> <meta class="elastic" name="es_thumbimage_rendition" content=""/> <meta name="es:thumbimage:src" content="https://www.utsouthwestern.edu/resources/images/UTSW_icon.jpg" /> <meta class="elastic" name="es_thumbimage_src" content="https://www.utsouthwestern.edu/resources/images/UTSW_icon.jpg" /> <meta name="es:keywords" content=""/> <meta class="elastic" name="es_keywords" content=""/> <meta name="es:contenttitle" content="Mineral Metabolism"/> <meta class="elastic" name="es_contenttitle" content="Mineral Metabolism"/> <meta class="elastic" name="es_mimetype" content="text/html; 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advances medical knowledge of the causes and treatments of these diseases; and educates physicians."> <meta name="twitter:creator" content="@UTSW"> <meta name="twitter:image:src" content="https://www.utsouthwestern.edu/resources/images/UTSW_icon.jpg"> <meta name="twitter:domain" content="https://www.utsouthwestern.edu/departments/mineral-metabolism/index.html"> <!-- end seo.ftl --><!-- begin /common/zf6/meta/link-styles.ftl --> <link rel="dns-prefetch" href="https://www.utsouthwestern.edu"> <link rel="dns-prefetch" href="https://use.fontawesome.com"> <link rel="preload" as="style" onload="this.rel = 'stylesheet'" href="https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,400;0,600;0,700;1,400;1,600;1,700&family=Roboto:ital,wght@0,300;0,400;0,500;0,700;1,300;1,400;1,500;1,700&display=swap"> <link rel="stylesheet" href='/css/animate.css?v=33897bb'> <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/6.4.2/css/all.min.css" integrity="sha512-z3gLpd7yknf1YoNbCzqRKc4qyor8gaKU1qmn+CShxbuBusANI9QpRohGBreCFkKxLhei6S9CQXFEbbKuqLg0DA==" crossorigin="anonymous" referrerpolicy="no-referrer" /> <link rel="stylesheet" type="text/css" media="all" href='/css/edu-3-desktop.css?v=50fdc43' /> <style> .twitter::before {content: "\e61b"; 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To ensure the best web experience, please upgrade to the latest standard browser for your computer.</p> </div> <div class="large-10 columns"> <a class="button small outline mt2 mb0" href="//www.microsoft.com/en-us/download/internet-explorer-11-for-windows-7-details.aspx">Upgrade your browser</a> </div> </div> </div> <![endif]--> <!-- begin patientcare-emergency component --> <!-- end patientcare-emergency component --> <header data-elastic-exclude id="header_site" class="header--site" role="banner"> <div class="header__block--site"> <div class="header--brand" itemscope itemtype="http://schema.org/Organization"> <!-- Begin zf6-brand component /webscripts/global/zf6/header/zf6-brand.get.html.ftl --> <div class="block--logo"> <a itemprop="url" href="https://www.utsouthwestern.edu"> <img class="left" itemprop="logo" src="/img/branding/utsw-edu-logo.svg" alt="UT Southwestern Medical Center" width="240" /> <span class="show-for-sr show-on-hover">Back to <br><b>UT&nbsp;Southwestern&nbsp;Home</b></span> </a> </div> <!-- End zf6-brand component --> <div class="block--flag hide-for-print"> <a href="/departments/"> <p>Departments & Centers</p> <span class="show-for-sr show-on-hover">Back to <br><b>Departments & Centers</b></span> </a> </div> <div class="block--menu hide-for-print"> <button class="button dropdown" type="button" data-toggle="nav_eyebrow"> <span class="show-for-sr">UT Southwestern Sites</span> </button> </div> <!-- Begin zf6-eyebrow-nav component /webscripts/global/zf6/navigation/zf6-eyebrow-nav.get.html.ftl --> <div data-elastic-exclude id="nav_eyebrow" class="dropdown-pane" id="examp |
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On line 609, column 9 -pane" id="example-dropdown" data-dropdown data-auto-focus="true"> <ul class="menu vertical"> <li><a href="https://www.utsouthwestern.edu"><span class="fa fa-home" aria-hidden="true"></span>&nbsp;UT Southwestern Home</a></li> <li > <a href="/index.html">Home - EDU</a> </li> <li > <a href="/research/">Research</a> </li> <li > <a href="/education/">Education & Training</a> </li> <li > <a href="https://utswmed.org/">Patient Care</a> </li> <li > <a href="https://profiles.utsouthwestern.edu">Faculty</a> </li> <li > <a href="/departments/">Departments & Centers</a> <ul class="menu vertical nested"> </ul> </li> <li > <a href="/media-hub/">Media Hub</a> </li> <li > <a href="https://jobs.utsouthwestern.edu/">Careers</a> </li> <li > <a href="/about-us/">About Us</a> </li> <li > <a href="/employees/">For Employees</a> </li> </ul> </div> </div> <!-- Begin zf6-appsearch-search component /webscripts/global/zf6/header/zf6-appsearch-search.get.html.ftl --> <div class="header--search" role="search"> <form method="post" action="/_elasticsearchappsearch" id="SearchForm" class="clearfix" title="Search EDU keyword or name."> <div class="input-group"> <input type="hidden" name="sortBy" value=""/> <input type="hidden" name="page" value=""/> <input type="search" name="q" placeholder="Search this site" title="Search this site" value="" id="search" class="text-input"> <div class="input-group-button"> <select name="site" id="site" aria-label="Select a search filter"> <option value="utsw_all_content" >All</option> <option value="utswmed_all" >Patient Care</option> <option value="edu_education_training" >Education &amp; Training</option> <option value="edu_research" >Research</option> <option value="utsw_faculty" >Faculty</option> <option value="edu_depts_centers" >Departments &amp; Centers</option> <option value="edu_newsroom" >Newsroom</option> <option value="edu_events" >Events</option> <option value="edu_aboutus" >About Us</option> <option value="edu_employees" >Employees</option> </select> </div> <div class="input-group-button"> <input type="submit" name="Search" value="Search" class="button" > </div> </div> </form> </div> <!-- End zf6-appsearch-search component --> </div> </header> <!-- Begin zf6-breadcrumb component /webscripts/global/zf6/navigation/zf6-breadcrumb.get.html.ftl --> <nav data-elastic-exclude id="breadcrumb" class="nav--breadcrumb" aria-label="You are here:" role="navigation"> <div class="nav__block"> <ul class="breadcrumbs"> <li><a href="/">Home</a></li> <li><a href="/departments/">Departments & Centers</a></li> <li><span class="show-for-sr">Current:</span><a href="/departments/mineral-metabolism/">The Charles and Jane Pak Center for Mineral Metabolism and Clinical Research</a></li> </ul> </div> </nav> <!-- End zf6-breadcrumb component --><!-- Begin zf6-micro-nav component /webscripts/global/zf6/navigation/zf6-micro-nav.get.html.ftl --> <nav data-elastic-exclude id="nav_micro_site" class="nav--micro-site"> <div class="nav__block"> <p class="nav__title"><a href="/departments/mineral-metabolism/">The Charles and Jane Pak Center for Mineral Metabolism and Clinical Research</a></p> <ul class="menu"> <li class=""><a href="/departments/mineral-metabolism/who-we-are/">Who We Are</a></li> <li class=""><a href="/departments/mineral-metabolism/laboratories/">Laboratories</a></li> <li class=""><a href="/departments/mineral-metabolism/patient-care/">Patient Care</a></li> <li class=""><a href="/departments/mineral-metabolism/research/">Research</a></li> </ul> </div> </nav> <!-- End zf6-micro-nav components --> <div class="page__block--main"> <!--googleon: all--> <!--searchindex-on--> <main id="page_main" class="page__main"> <div class="main__block"> <div id="main_header" class="main__header"> <!-- Begin alert-block component /webscripts/template/zf6/contents/zf6-alert-block.get.html.ftl --> <!-- End alert-block components --> <!-- Begin zf6-slider component /webscripts/template/zf6/widgets/zf6-slider.get.html.ftl default on --> <div class="swiper-container slider-autoheight slider-loop"> <div class="swiper-wrapper slides"> <div class="slide utsw-slider-v2 utsw-slider-v2--modal-trigger"> <div class="slide__content"> <img src="/asset/464325cd-5be8-4662-8b62-90f3f6de52e7/GettyImages-626957031-compressed.jpg" alt="GettyImages-626957031-compressed.jpg"> <div class="slide__text"> </div> </div> </div> </div> </div> <!-- End zf6-slider components --> </div> <article class="page__article article"> <!-- Begin zf6-content-header component /webscripts/template/zf6/contents/zf6-content-header.get.html.ftl --> <!-- End zf6-content-header components --> <div class="article__main"> <!-- End zf6-social component --> <!-- Begin zf6-content component /webscripts/template/zf6/contents/zf6-content.get.html.ftl --> <h2>What is Mineral Metabolism?</h2> <p>Minerals make up a large portion of our body and are constantly and actively turned over (metabolism). They are essential for a variety of functions of cells, tissues, and organs. Disturbances of these normal processes result in diseases of mineral metabolism. These disorders can be caused by too little or too many minerals, minerals not being turned over at the appropriate speed, and minerals ending up in the wrong places. Considerable expertise is required to diagnose and treat these disorders and that is often best done in centers where cutting-edge research is being conducted.</p> <p>&nbsp;</p> <h2>Diseases of Mineral Metabolism</h2> <h3>Common diseases</h3> <ul class="column-double"> <li> <p>Kidney stone disease</p> </li> <li> <p>Osteoporosis</p> </li> <li> <p>Bone complications in kidney disease</p> </li> <li> <p>Parathyroid disease (hyperparathyroidism and hypoparathyroidism)</p> </li> <li> <p>Cancer-related bone disease</p> </li> </ul> <h3>Uncommon diseases</h3> <ul class="column-double"> <li> <p>Hypercalcemia and hypocalcemia</p> </li> <li> <p>Hypermagnesemia and hypomagnesemia</p> </li> <li> <p>Hyperphosphatemia and hypophosphatemia</p> </li> <li> <p>Hypophosphatasia</p> </li> <li> <p>Osteomalacia</p> </li> <li> <p>Paget&rsquo;s disease</p> </li> <li> <p>Nephrocalcinosis</p> </li> <li> <p>Osteogenesis imperfecta</p> </li> <li> <p>Distal renal tubular acidosis</p> </li> <li> <p>Proximal renal tubular acidosis</p> </li> <li> <p>Bartter&rsquo;s syndrome</p> </li> <li> <p>Gitelman&rsquo;s syndrome</p> </li> <li> <p>Dent&rsquo;s disease</p> </li> <li> <p>Renal phosphate wasting</p> </li> <li> <p>Fanconi&rsquo;s syndrome</p> </li> <li> <p>Cushing&rsquo;s disease</p> </li> <li> <p>Addison&rsquo;s disease</p> </li> </ul><!-- End zf6-content components --> </div> <aside class="article__aside hide-for-print"> <!-- Begin zf6-callout-block component /webscripts/template/zf6/widgets/zf6-callout-block.get.html.ftl --> <!-- End zf6-callout-block components --><!-- Begin zf6-quicklink component /webscripts/template/zf6/widgets/zf6-quicklink.get.html.ftl --> <!-- End zf6-quicklink components --> <!-- Begin zf6-callout1 component /webscripts/template/zf6/widgets/zf6-callout1.get.html.ftl --> <div class="callout callout--one"> <h2>Director</h2> <div class="figure"><img src="/media/2400-callout-moe-2011-2095.jpg" alt="Orson W. Moe, M.D." width="209" height="300" /></div> <p><a href="http://profiles.utsouthwestern.edu/profile/15030/">Orson W. Moe, M.D.</a> <br />Director,&nbsp;Charles and Jane Pak Center for Mineral Metabolism and Clinical Research</p> <p><strong>Medical School:&nbsp;</strong>University of Toronto</p> <p><strong>Residencies:&nbsp;</strong>Internal Medicine and Surgery, University of Toronto</p> <p><strong>Fellowship:&nbsp;</strong>Nephrology, University of Toronto; Renal Physiology, UT Southwestern</p> </div> <!-- End zf6-callout1 components --> <!-- Begin zf6-callout2 component /webscripts/template/zf6/widgets/zf6-callout2.get.html.ftl --> <!-- End zf6-callout2 component --> <!-- Begin zf6-callout3 component /webscripts/template/zf6/widgets/zf6-callout3.get.html.ftl --> <!-- End zf6-callout3 components --><!-- Begin zf6-callout4 component /webscripts/template/zf6/widgets/zf6-callout4.get.html.ftl --> <!-- End zf6-callout4 components --><!-- begin zf6-bametrics component /webscripts/template/zf6/widgets/zf6-bametrics.get.html.ftl--> <!-- end zf6-bametrics component --> </aside> </article> </div><!-- @end main__block --> <div class="anchors"> <!-- Begin zf6-sticky-anchor-block component /webscripts/global/zf6/footer/zf6-sticky-anchor-block.get.html.ftl --> <!-- End zf6-sticky-anchor-block components --> <a class="button button--top" href="#page"><span class="fa fa-arrow-up" aria-hidden="true"></span><span class="show-for-sr">Back-to top</span></a> </div> </main><!-- @end page__main --> <!--googleoff: all--> <!--searchindex-off--> </div> <!-- Begin zf6-internal-request component /webscripts/global/zf6/footer/zf6-internal-request.get.html.ftl default on --> <!-- End zf6-internal-request components --> <footer data-elastic-exclude id="siteFooter" class="site-footer" role="contentinfo"> <!-- Begin micro-footer component /webscripts/template/resp/widgets/micro-footer.get.html.ftl --> <div class="footer__section"> <div class="section__block"> <h3>Institution</h3> <div class="footer__block"> <ul class="list-links"> <li><a title="Research info for the university" href="/research/">Research</a><br /> <ul> <li><a href="https://clinicaltrials.utswmed.org/">Clinical Trials</a></li> <li><a href="/research/core-facilities/">Core Facilities</a></li> <li><a href="/research/ctsa/">CTSA Program</a></li> <li><a href="/research/research-support/">Research Administration</a></li> <li><a href="https://www.utsouthwestern.edu/labs/">Research Labs</a></li> <li><a href="/research/programs/">Research Programs</a></li> <li><a href="/research/scientific-discoveries/">Scientific Discoveries</a></li> <li><a href="/about-us/administrative-offices/technology-development/">Technology Development</a></li> </ul> </li> </ul> </div> <div class="footer__block"> <ul class="list-links"> <li><a title="Education and Training info for the university" href="/education/">Education &amp; 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